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Hello there @spice, I'm also not true joyful about taking prednisone for the second time around with my polymyalgia rheumatica (PMR) but it's very much the only point that makes the pain, stiffness and inflammation go away. I started at 20 mg last year in September and am now at 3 mg having attempted twice to drop to 2.5 mg. My last round with PMR